Stop Manually Reviewing Certificates of Analysis

Longi Engineering’s AI-powered COA automation reads, extracts, validates, and reports lab data in minutes eliminating hours of manual document review for biotech and pharma quality teams.

70%

Reduction in manual
review time

45 min

Average COA
processing time

90%+

Data extraction
accuracy

25+

COA formats
supported
 

What Does COA Automation Do?

COA automation uses artificial intelligence specifically document AI and machine learning to automatically read Certificate of Analysis documents, extract all relevant data fields, validate results against specifications, and push structured data into downstream systems. It eliminates manual steps entirely for routine COAs, and reserves human review only for genuine exceptions.

Key capabilities of a COA automation solution include:

  • Intelligent extraction of product name, lot and batch number, test parameters, and results from unstructured PDFs
  • Automatic comparison of extracted results against approved specifications and acceptance criteria
  • Routing of out-of-specification results for immediate human review and escalation
  • Integration with ERP, LIMS, and quality management systems for seamless data flow
  • Digital filing, indexing, and search of all COA records for instant retrieval during audits.

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Manual COA review is costing your team time, money, and compliance risk

Biotech and pharma quality teams spend thousands of hours annually on a process that AI can handle in minutes. Here’s the reality of manual COA management.

30–90 Minutes Per Document

Staff manually opens each COA PDF, reads test parameters, compares against specs, and re-enters data into spreadsheets or ERP systems one document at a time, every day.

High Risk of Human Error

Copy-paste mistakes in critical safety and efficacy data can trigger compliance failures, batch rejections, regulatory findings, and costly product recalls.

Documents Scattered Everywhere

COAs buried across email inboxes, shared drives, and paper files make pre-audit preparation a multi-day scramble and slow down regulatory reporting.

No Path to Scale

As your product portfolio and supplier network grow, COA volume grows with it. Manual processes don't scale organizations end up hiring more people just to perform additional data oversight.

Audit Preparation Takes Days

Preparing COA records for audits and quality reviews can take weeks when done manually. An automated system drastically reduces the time required, making audit preparation faster and more efficient.

$150K+ in Hidden Labor Costs

Mid-size pharma and biotech organizations typically spend over $250,000 annually in fully loaded labor costs for manual COA processing—budget that belongs in research, not data validation.

See It in Action

Watch Our AI Process a COA in Minutes

See exactly how our AI reads a Certificate of Analysis, extracts all critical data fields, validates against your specifications, and delivers a clean structured report without a human in the loop.

01

Upload any COA PDF, scanned image, or email attachment in any format from any lab or supplier

02

AI reads every field: product name, lot number, test parameters, and results automatically.

03

Validated, structured data is ready for your ERP, LIMS, or compliance system in minutes, not hours

How It Works

From document to decision-ready data in 4 steps

A fully automated COA workflow that replaces manual review with intelligent AI processing  no template setup, no configuration headaches.

Receive COA

COAs arrive via email, supplier portal, upload, or API integration. Any format, any lab, any supplier — accepted automatically.

AI Extracts Data

Our AI reads the document and identifies all key fields — product name, lot number, test parameters, results, and specifications — with 90%+ accuracy.

Validate & Flag

Results are cross-checked against your specifications. Out-of-spec values are instantly flagged for human review — everything else passes automatically.

Report & File

Structured data flows into your ERP, LIMS, or QMS. Batch reports and compliance documentation are generated and filed automatically.

Capabilities

Everything your team needs to automate the entire COA workflow

Purpose-built for the precision and compliance demands of pharma and biotech not adapted from a generic document processing tool.

Intelligent Document Reading

Processes COAs from PDFs, scanned images, emails, and spreadsheets. Handles any format or layout from any supplier without template configuration.

90%+ Extraction Accuracy

Advanced AI models trained specifically on laboratory and quality documents achieve near-perfect data extraction — eliminating the error risk of manual entry for safety-critical data.

Smart Validation Rules

Automatically cross-checks extracted results against your specifications and acceptance criteria. Only genuine exceptions are routed for human review — freeing your team for real quality decisions.

ERP & LIMS Integration

Connects seamlessly with SAP, Oracle, LabVantage, Veeva, Microsoft Dynamics, and more. Validated data flows directly where you need it — no manual export or re-entry required.

Instant Search & Retrieval

Find any COA in seconds by product, supplier, lot number, date, or test parameter. No more digging through email folders or shared drives before an audit.

Automated Report Generation

Generate batch reports, supplier quality summaries, and compliance documentation automatically — ready for internal review or regulatory submission, including FDA 21 CFR Part 11 environments.

Industries Served

Built for regulated industries that depend on COA accuracy

Our COA automation solution serves organizations across the life sciences and regulated manufacturing sectors.

Pharmaceutical Manufacturing

Automate incoming raw material COA review, batch release documentation, and GMP compliance reporting.

Biotech & Life Sciences

Process COAs for reagents, cell culture media, APIs, and biological materials at any scale of operations.

Contract Research Organizations

Handle high-volume COA workflows from multiple clients and suppliers without increasing headcount.

Nutraceuticals & Supplements

Verify raw ingredient quality and maintain complete traceability documentation for regulatory compliance.

Specialty Chemicals

Automate incoming quality inspection documentation and supplier COA management across your supply chain.

Medical Device Manufacturers

Ensure component COAs are validated and filed to meet ISO 13485 and FDA quality system regulations.

Some Of Our 300+ Satisfied Clients

Hear From Our Happy Clients

Don’t take our word for it. Here is what a few of our current clients have to say about us.

Frequently Asked Questions about COA automation

Does the AI work with our specific COA formats?

Yes. Our AI does not rely on fixed templates. It reads COAs from any layout, supplier, or laboratory — whether clean digital PDFs, scanned paper documents, or structured spreadsheet exports. It adapts to new formats automatically without manual reconfiguration.

Most implementations are live within 2 to 4 weeks. We handle system configuration, integration with your ERP or LIMS, staff onboarding, and validation documentation. Our team manages the process end-to-end so your internal team stays focused on their day-to-day work.

We have pre-built integrations with SAP, Oracle, LabVantage, IDBS, Veeva Vault, Microsoft Dynamics, and a range of other platforms. For less common systems, we build a custom connector during the implementation phase.

When the AI detects a test result outside your defined acceptance criteria, it immediately flags the document and routes it to the appropriate team member for review. Everything in-specification is processed without human involvement — keeping your team focused on genuine quality issues.

Regulatory compliance is a core design principle, not an add-on. The system maintains a full audit trail of all document processing actions, supports electronic signature workflows, and produces documentation suitable for GMP and FDA inspection readiness. We work with your quality team to validate the system appropriately for your regulatory context.

The system applies confidence scoring to every extraction. When confidence falls below a defined threshold, the document is automatically flagged for human verification. On average, this represents fewer than 10% of total COA volume — meaning 90%+ of documents are processed without any human involvement.

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